How to Improve Your Memory & Cognitive Function at Any Age | Dr. Alan Castel
Key insights
Books referenced
- Better With Age: The Psychology of Successful Aging - Alan Castel - Castel's own book, published this year, and the throughline for the whole episode's discussion of successful aging and super-agers.
- Protocols: An Operating Manual for the Human Body - Andrew Huberman - Huberman's own forthcoming book, plugged at the end of the episode; available for presale.
- Steve Jobs - Walter Isaacson - Cited while discussing whether Jobs had some deeper sense he wouldn't live long, given the intensity with which he lived and built.
- Principles of Neurobiology - Liqun Luo - Huberman mentions rereading his colleague's textbook cover to cover and finding unexpected enrichment in revisiting foundational material.
- Principles of Neural Science - Eric Kandel et al. (Columbia) - Mentioned as the more established, larger comparison textbook to Luo's newer one.
Media referenced
- Sully - movie - Referenced as the story of pilot Chesley Sullenberger's Hudson River water landing, used as an illustration of wisdom as accumulated knowledge deployed at the right moment.
- Dean Potter documentary (four-part series) - show - Huberman describes a scene of a base jumper dying after using unfamiliar borrowed gear, illustrating how trained people default to habitual routines under extreme arousal.
- Huberman Lab episode with Andrew Huberman's father - podcast - Castel calls it his favorite recent episode of the podcast, for showing the dynamic between an older and younger generation.
Companies
- Wealthfront - Sponsor; cash account and investing platform.
- Helix Sleep - Sponsor; customized mattresses, Huberman personally uses the Dusk model.
- AG1 - Sponsor; vitamin/mineral/probiotic supplement.
- Function Health - Sponsor; 160+ biomarker lab testing membership.
- Lingo - Sponsor; continuous glucose monitor (Abbott).
Techniques and frameworks
- Desirable difficulties / errorful learning - Deliberately struggling to recall something (e.g. drawing the Apple logo from memory before looking at it) produces stronger learning than passive repeated exposure.
- Levels of processing / deep semantic encoding - Learning material by engaging with how it functions or interacts (verbs, not labels) rather than rote-memorizing labels produces more durable understanding.
- Retrieval practice and self-testing, including AI-generated quizzes - Testing yourself on material, including having an AI tool generate a self-test, is one of the most effective ways to learn versus rereading or highlighting.
- Single-leg balance test - Standing on one leg for 10+ seconds, then with eyes closed, as a quick self-assessment of fall risk; balance is trainable in a month or two via yoga or Tai Chi.
- ABCs of successful aging - Castel's framework from his book: Attitude/Adapt (a positive, agentic view of aging), Balance (physical and life balance), and Connection (fewer, higher-quality relationships).
- Selective optimization with compensation - Developmental theory describing how older adults narrow their range of activities to focus effort on the few things that matter most to them.
- Socio-emotional selectivity theory - Laura Carstensen's theory that a shortened perceived time horizon shifts priorities toward emotionally meaningful goals and relationships, regardless of chronological age.
Summary
Andrew Huberman interviews UCLA psychology professor Dr. Alan Castel, a memory and cognitive-aging researcher and author of the new book "Better With Age," about what actually determines whether we remember something, and why cognitive decline with age is far less inevitable and far more nuanced than commonly assumed. The conversation opens on the mechanics of memory itself: Castel argues that good learning happens through productive failure, not repetition, illustrated by the well-known finding that people who have seen the Apple logo thousands of times still can't accurately recall its details unless forced to retrieve it from memory first. This extends into a discussion of memory's fundamentally reconstructive nature, using the Ronald Cotton wrongful-conviction case to show how eyewitness identification can permanently overwrite the original memory of an event, and how the same reconstructive machinery underlies both remembering the past and imagining the future.
The middle of the episode turns to everyday and prospective memory (Huberman's habit of memorizing hotel fire escape routes, both hosts' stories of fire alarms and near-disasters), and to how extreme arousal causes even highly trained people to default to ingrained habits rather than careful reasoning, illustrated by a base-jumping death captured on film. From there the conversation moves into the biology and psychology of aging directly: a randomized walking study that grew hippocampal volume by roughly 1% and improved memory a year later, the underappreciated importance of balance training for fall prevention, and the finding that subjective age (how old you feel) predicts longevity better than chronological age.
The back half of the episode is organized around Castel's research on "super-agers," older adults whose cognitive performance rivals people decades younger, and his ABCs framework for successful aging: Attitude/Adapt, Balance, and Connection, distilled partly from an interview with UCLA basketball coach John Wooden, who told Castel the two most important words in life were love and balance (and who, in a sobering irony, later died some years after a fall he didn't report because of pride). Castel and Huberman discuss socio-emotional selectivity theory, the surprising finding that older adults showed more psychological resilience than younger adults during COVID-19, and a positivity bias that emerges with age and may explain both repeated storytelling and the U-shaped happiness curve across the lifespan, with midlife as the dip.
The episode closes on more applied territory: how curiosity about specific topics can increase with age even as general curiosity declines, protecting memory for material people already care about; how AI voice-cloning has made fraud targeting older adults substantially more dangerous by exploiting their socio-emotional focus on family; and a broader meditation on wisdom versus knowledge, using pilot Chesley Sullenberger's Hudson River landing as an example of wisdom as accumulated experience deployed correctly under pressure. Castel repeatedly returns to intergenerational connection, curiosity, and a sense of purpose as the through-lines of aging well, over any single biohacking intervention.
Notable Quotes
"Memory is really a mental representation of the past, and by its very nature, it's reconstructive." - Dr. Alan Castel
"The best way to remember something is, again, failures." - Dr. Alan Castel
"The past is more unpredictable than the future." - Andrew Huberman, quoting a Russian proverb via Morgan Housel
"Subjective age is a better predictor of how long you'll live than your biological age." - Dr. Alan Castel
"The two most important words in the English language...love [and] balance." - John Wooden, as recounted by Dr. Alan Castel